以两组随机对照试验为例:
delta:预计干预后干预与对照的差值
sigma:预计的标准差
d:预计的效应量effect size
n:样本量
公式:
$$n=\frac{4(Z_\alpha+Z_\beta)^2\sigma^2}{\Delta^2}$$
library('pwr')
delta <- 3
sigma <- 5
d <- delta/sigma
pwr.t.test(d=d, sig.level=.05, power = .90, type = 'two.sample')
输出结果:
Two-sample t test power calculation
n = 59.35155
d = 0.6
sig.level = 0.05
power = 0.9
alternative = two.sided
NOTE: n is number in *each* group
参考文献:https://www.r-bloggers.com/calculating-required-sample-size-in-r-and-sas/